Can my wife get pregnant if im on steroids
To describe self-reported medication patterns and fertility rates in a population of anabolic steroid AS users. We reviewed data from an online survey of AS users and identified a sub-group who had attempted to achieve a pregnancy with their partners while using AS. The online survey consisted of questions addressing demographics, AS use, ancillary medications, and fertility outcomes. A total of 97 men of total respondents had attempted to achieve a pregnancy while taking AS and comprise the current cohort.SEE VIDEO BY TOPIC: What is the purpose of steroid shots during pregnancy?
- The Silent Shame of Male Infertility
- Anabolic Steroids and their Effect on Male Fertility
- How Medications Can Affect Your Fertility
- Public Enemy #1 for Male Fertility: Anabolic Steroids
- Steroid Use and Male Fertility
- Medication patterns and fertility rates in a cohort of anabolic steroid users
- Drugs and Male Fertility
The Silent Shame of Male Infertility
To describe self-reported medication patterns and fertility rates in a population of anabolic steroid AS users. We reviewed data from an online survey of AS users and identified a sub-group who had attempted to achieve a pregnancy with their partners while using AS.
The online survey consisted of questions addressing demographics, AS use, ancillary medications, and fertility outcomes.
A total of 97 men of total respondents had attempted to achieve a pregnancy while taking AS and comprise the current cohort.
The majority of men were 25—44 years old Ancillary drug use was common with only 5. The most common reported ancillary drugs were antiestrogens The fertility rate was Interestingly, only Age at initiation of AS use, maximum dosage utilized, yearly duration of supplementation, and number of years using steroids were not associated with a prolonged duration to pregnancy or decreased rate of pregnancy.
This is presumably related to cycling of therapy and concomitant use of fertility preserving medications. Anabolic steroid AS use is common with a 6.
Adverse effects of AS are well reported and occur in a dose-dependent fashion 3. The general effect on the male reproductive system is that of central suppression of gonadotropins. Downstream sequelae include decreased endogenous testosterone production, testicular atrophy, and impaired spermatogenesis.
Recognition of the contraceptive potential of androgens dates back as early as , with multiple contemporary randomized controlled trials confirming suppression of spermatogenesis with androgen supplementation 4.
Despite the known contraceptive effect of androgens, spontaneous pregnancies while using AS are often reported within online communities of users. To reduce hypothalamic-pituitary-gonadal HPG suppression, men taking AS commonly employ medical augmentation protocols that maintain low levels of spermatogenesis during a cycle of AS and augment recovery of the HPG axis and spermatogenesis following cessation of the cycle 5 - 8.
To date, no studies have specifically evaluated paternity rates among men taking supra-physiologic doses of AS. Given the paucity of data and increasing interest in the concept of augmentation strategies to maintain fertility while administering testosterone for cases of male infertility and hypogonadism, we sought to describe the fertility status and medication usage in a cohort of AS users. Following institutional review board approval, nine anonymous websites were identified using Google www.
Moderators of each website were contacted regarding the aims, confidentiality, inclusion criteria, and survey questions of the study. With their approval, a brief description of the study and anonymous link to a survey was posted on the main forum or in the AS sub-forum, if available.
The survey was created using Survey Monkey www. All data was gathered in an anonymous fashion and participants were not incentivized to take the survey. Informed consent was placed on the first page of the survey and agreed to upon answering 3 inclusion criteria questions. Incomplete surveys and men receiving testosterone supplementation under the guidance of a physician were excluded from analysis.
Of the men completing the survey, a subset of those who had attempted to achieve a pregnancy during AS use was reviewed and comprises the current study cohort. The questionnaire included 49 items and took on average, 5—10 minutes to complete. All questions were voluntary with the option to skip a question or end the survey at any time.
No incentives were provided to complete the survey. Survey data included: demographics, participation in sports, details of testosterone and other performance enhancing drug use, medical conditions, side effects while on and off AS, fertility, and sexual function related questions. A total of participants were anonymously polled in a self-reporting fashion.
Sixty-six were excluded for not meeting inclusion criteria, 26 surveys were incomplete, and had not attempted to have children. Demographics of the cohort are listed in Table 1. The majority of AS users were 25—44 years old Current or previous collegiate athletes represented Common reasons for initiating testosterone included gains in muscle mass Interestingly, a desire to attract women 2.
See Table 2 for a list of self-reported reasons for AS use. The majority of survey respondents reported AS use for greater than one year Continuous utilization was also high, with Dosing and AS utilization patterns are described in Table 3.
The most frequently reported ancillary drugs were antiestrogens and sexual enhancement medications SEMs SEMs included phosphodiesterase inhibitors and dopamine agonists e. PCT was utilized by Additional details of ancillary drug usage are outlined in Table 4. A total of Eighteen participants Among 32 men who were actively using testosterone while attempting to achieve a pregnancy, 29 Age at initiation of testosterone, number of years utilizing, maximum dosage, and number of weeks per year utilized were not associated with duration required to achieve pregnancy or rate of achieving pregnancy.
When considering demographic variables, age, employment status, income, level of education, and marital status were also not associated with the rate of successful pregnancy. Full details of fertility in AS users are outlined in Table 5. We report, to our knowledge, the first description of self-reported paternity rates and patterns of fertility preserving medication use in the AS user population. Conception at one year in our cohort reached This subset did not report longer durations to achieve conception or increased difficulty achieving pregnancy.
These numbers are further supported by modest rates of fertility evaluation Surprisingly, statistical analysis failed to demonstrate any significant associations between successful pregnancy and testosterone frequency of use, dose, or specific agents used to mitigate side effects of therapy such as antiestrogens. The only significant association identified was a longer duration of testosterone use among men who achieved a pregnancy while on testosterone compared to those that were between cycles of AS.
This likely reflects the finding that older men had longer durations of testosterone use overall and were more likely to attempt to achieve a pregnancy during that time period as compared to their younger counterparts. The HPG axis is variably suppressed following administration of exogenous testosterone 10 , Eleven participants also experienced an escape phenomenon with restoration of sperm in the ejaculate despite supra-physiologic testosterone levels.
Recovery of the HPG axis appears to be reliable and predictable across a large population. Despite decreases in sperm count, TE does not appear to affect sperm function, morphology, or motility in men with normal semen parameters A small retrospective series suggests a dose independent and incomplete suppression of spermatogenesis with AS Despite steroid doses up to 40 times higher than clinical application, only 24 displayed subnormal sperm counts. Those without exposure in the previous 4 months were normospermic Other case reports support recovery of normal sperm levels within 1 year of abstinence despite previously excessive doses of AS 16 , Based on these prior reports of suppression of the HPG axis with testosterone, one would expect lower rates of pregnancy in AS users.
The relatively high rate of preservation is likely secondary to the common practice of AS users to include adjunctive therapies along with testosterone or to include washout periods between intervals of AS use cycling. Often, the primary objective is not maintenance of fertility, but to prevent adverse effects of AS withdrawal including muscle loss, loss of libido, erectile dysfunction, and impaired mood There is currently very limited data available on the impact of combining testosterone and secondary therapies on fertility outcomes.
Karila and colleagues reported on a series of 18 healthy male power athletes utilizing massive doses of AS concomitant with HCG 6. Semen analysis was checked at the end of the cycle as well as 1. By six months all had recovered normal sperm counts and semen parameters.
HCG administration maintained spermatogenesis, likely via maintenance of intratesticular testosterone levels, despite massive doses of exogenous hormones. However, no data were obtained on the percentage of men attempting to achieve a pregnancy during or following the study.
Maintenance of spermatogenesis and intratesticular testosterone levels has also been reported with HCG and AIs in the presence of exogenous testosterone administration in the hormone replacement therapy population 7 , 19 , These studies suggest a possible mechanism for the preserved fertility rates among our cohort of men.
Our study has several notable limitations including the non-validated survey based format with associated sampling and recall bias. Data are also dependent upon the accuracy of participant reports and may be confounded by participants wishing to demonstrate that their practices are more benign than might otherwise be expected.
Despite these limitations, the current study provides demographics, patterns of utilization, and fertility outcomes from a large sampling of AS users who have pursued pregnancy. Fertility rates are maintained in a population of AS users and are relatively equivalent to age-matched historical controls. Conflicts of Interest : The authors have no conflicts of interest to declare.
National Center for Biotechnology Information , U. Journal List Transl Androl Urol v. Transl Androl Urol. Ross A. Avant , Cameron M. Charchenko , Manaf Alom , Mary E. Author information Article notes Copyright and License information Disclaimer. Corresponding author. Correspondence to: Landon Trost, MD. Email: ude. Received Apr 22; Accepted May 2. Copyright Translational Andrology and Urology.
All rights reserved. Abstract Background To describe self-reported medication patterns and fertility rates in a population of anabolic steroid AS users. Methods We reviewed data from an online survey of AS users and identified a sub-group who had attempted to achieve a pregnancy with their partners while using AS.
Anabolic Steroids and their Effect on Male Fertility
Many men do not realize that the testosterone they are taking to improve their appearance can seriously affect their fertility and overall health. They may not know that using a steroid such as testosterone to build muscle mass can cause low sperm counts or even the absence of sperm. In most cases, Ovation partner physicians view this problem as treatable.
B radley Goldman has filled out a size large T-shirt his whole adult life. As a bodybuilder, he knew that a steady stream of lean, bland proteins, heavy weights and steroids would make his muscles pop. But over the past six months, Goldman, a fitness and nutrition consultant in Los Angeles, has watched his jacked physique soften and shrink. He tried it on for his wife Brittany, and it hung loose on his frame. He knew she saw the changes too.
How Medications Can Affect Your Fertility
Men who wish to father a child should talk to their doctor before starting a new medication or having any treatments. Non-FDA approved male fertility supplements may be widely advertised as fertility enhancers but they have not been scientifically evaluated and may cause harm. Before you take any supplements it is important to discuss it with a healthcare provider. Men who are having trouble fathering a child should speak to their doctor about the medications they are taking, and the possible need for semen tests. Some men may have an unexpected side effect from a medication that can harm their fertility. If your doctor thinks that this may be the case, it may be a good idea to stop the medication or try a different one. You should always discuss this decision with the doctor who prescribed the medication.
Public Enemy #1 for Male Fertility: Anabolic Steroids
Your fertility may drop if you're taking certain medicines. Your body is an important vessel—one you want to keep in tip-top shape if you're considering a pregnancy. Women who are planning a family may already know that sexually transmitted diseases, fibroids, excessive weight, and thyroid conditions among other things can all impact conception. But less familiar is the fact that certain over-the-counter and prescription medications may also affect fertility. But some medications are necessary to treat certain conditions, leaving women to grapple with both the possible inability to conceive and the difficult feelings, including sadness, isolation, frustration, and anger, that can accompany it.
Guidelines consider steroids taken during pregnancy to be of low risk to babies. Steroids are generally considered safe for use by breast feeding mothers. Although a small amount of the drug may pass to the baby, studies have found no harmful effects.
Steroid Use and Male Fertility
Medication patterns and fertility rates in a cohort of anabolic steroid users
Drugs and Male Fertility